Searchable abstracts of presentations at key conferences in endocrinology

ea0084op-11-53 | Oral Session 11: Young Investigators / Basic | ETA2022

CD3+CD8+CD20+ T cells as a marker of the inflammatory phase in thyroid autoimmune and related polyautoimmune disorders: a pilot study

Stramazzo Ilaria , Virili Camilla , Capriello Silvia , Brusca Nunzia , Flavia Bagaglini Maria , Romeo Giovanna , Mangino Giorgio , Centanni Marco

Objectives: Human CD3+CD20+ T cells represents 3-5% of circulating T cells and may be detected in all lymphatic organs and in the cerebrospinal fluid. In healthy individuals CD3+CD20+ T cells have been shown to produce higher levels of IL-17A and/or IFN-γ than those of CD3+CD20- T cells. Some reports described the role of CD3+CD20+ T cells in autoimmune disorders such as multiple scler...